The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. This could result in elevated levels of creatine kinase in blood serum when, in fact, there was no underlying medical condition.23. Use the following article to inform yourself about everything that you need to know about the CPK blood test and the importance of CPK test normal range. Stress-free visits The CPK blood test is also commonly used to detect the presence of the gene responsible for the development of muscular dystrophy later in life. The journal Stroke reports that stroke sufferers often have elevated CK levels. Abnormal MRI does not exclude a neuromuscular disease. Muscular dystrophy is a group of genetic diseases that typically affects male children and will cause high CPK levels due to muscle loss. The most common cause of low creatine kinase levels is muscle wasting (muscle atrophy) due to physical inactivity, illnesses, or old age [85]. If your creatine kinase levels are high, your doctor may order a creatine kinase isoenzyme tests to determine which type of creatine kinase enzyme is high [1, 2]: There is still no universally agreed upon range for creatine kinase. 8600 Rockville Pike Information developed by A.D.A.M., Inc. regarding tests and test results may not directly correspond with information provided by UCSF Health. Testing for high CPK levels in a blood test is an important way for doctors to evaluate muscle damage in the body. When there is muscular damage, CPK leaks into the blood. By testing for levels of troponin (protein that is usually elevated after a heart attack) doctors can identify the possibility that it was stroke and not cardiac-related issue.7, Other reports suggest that the high levels of CK in blood serum after a stroke can help to determine the best way to treatpatients who had recently suffered a stroke.8. Learn how we can help. Increased CPK-1 levels usually indicate a brain injury due to stroke, brain bleed, brain cancer, seizure, etc. In dogs, both macroCK-2 and CK-BB (CK-1) were the next most frequent forms of CK, whereas in cats both macroenzymes were the second most frequent form. Athletes have more of this enzyme in their blood, but so do obese and overweight people. An official website of the United States government. Clin Chem.1994 Jul;40(7 Pt 1):1278-83. The cookie is set by GDPR cookie consent to record the user consent for the cookies in the category "Functional". Child Health Issues; Cpk mb meaning and normal range. was last modified: April 21st, 2018 by Jenny Hills, Nutritionist and Medical Writer. Unauthorized use of these marks is strictly prohibited. Lin JC, Apple FS, Murakami MM, Luepker RV. A mildly elevated CK (1-2x normal) should be followed up. The normal range is generally up to 250 U/L (units per liter) but varies by laboratory. Referral to a neurologist is warranted for children without improvement after 6 months. Afterward, there may be some throbbing. An underactive thyroid means that levels of thyroid hormone in your body are too low. Some labs use different measurements or test different samples. Kelley and Firestein's Textbook of Rheumatology. In children, elevated CK almost always reflects skeletal muscle damage. In a study of 442 people, people with low creatine kinase levels were 73% more likely to faint [91]. the 'CPK-screen' kitset (Antonik Laboratories) and a Chem-Glow photometer (American Instrument . This work represents an expansion in our knowledge base on pediatric reference ranges. Lycopene-rich tomatoes linked to lower stroke risk. 80th training command. 2003;107:e2-e5. Creatine kinase levels can be significantly reduced in autoimmune diseases, such as lupus and rheumatoid arthritis [86, 87, 88, 89]. Best in Northern CA A health care provider may also test for elevated liver enzymes when a child is feeling unwell. Exercise and training are the main cause of increased creatine kinase levels [10, 11, 12]. The 97.5th percentile of CK was 382 (95% CI 295-469) in white men, 1001 (95% CI 718-1284) in black men, 295 (95% CI 216-374) in white women, and 487 (95% CI 310-664) in black women. Here are some of the best ways that you can prevent cardiac-related health issues. What is a normal CPK level? Exercise can reduce levels of bad cholesterol, lower blood pressure, and lower insulin resistance.19, Consume more garlic. CK levels are particularly elevated in certain types of MD, such as Duchenne MD, and less elevated in others like Becker MD. Lose some weight if you are overweight. CK levels can be mildly elevated (~500 U/L) in neuropathies like Charcot-Marie-Tooth disease or anterior horn cell diseases like spinal muscular atrophy, or grossly elevated (~3,000 to >30,000 U/L) in Duchenne muscular dystrophy or some other muscular dystrophies. The CPK normal range for a male is between 39 - 308 U/L, while in females the CPK normal range is between 26 - 192 U/L. Henry's Clinical Diagnosis and Management by Laboratory Methods. Elevated CK values are found physiologically in children, pregnant women, and after exercise. Factors known to significantly affect the results: Reference ranges quoted above are based on studies in Caucasians, higher values are observed in black populations. When you have sudden chest pain, try to meet your physician within 3-8 hours of the onset of the pain. Creatine kinase (known previously as creatine phosphokinase or CPK) is distinct from creatinine and is a biomarker of muscle damage. CPK is an enzyme that is found within muscle cells. Normal reference values for serum CK-MB range from 3 to 5% (percentage of total CK) or 5 to 25 IU/L. They are continually monitored by our internal peer-review process and if we see anyone making material science errors, we don't let them write for us again. CPK-2 is found in the heart, and any increased CPK-2 levels are linked to an injury to the heart, a heart attack, inflammation of the heart muscle, etc. She believes that SelfHacked has the best science that is also layperson-friendly on the web. Of course, your doctor will run more tests to diagnose the underlying reasons for creatine kinase that is at abnormal levels. Note of warning: If transaminases (AST and ALT) are elevated, check CK. In Q wave (complete occlusion) (transmural) infarction, CK-MB average peak is 17 to 20 . This site needs JavaScript to work properly. Created for people with ongoing healthcare needs but benefits everyone. Elevated creatine kinase can be a sign of serious tissue damage or an underlying disease or disorder. Ask your provider what result is right for you. When the muscle cells are damaged for any reason, the CPK is released into the blood and the test is elevated. This is a medical emergency and patients should be referred to the nearest Emergency Department immediately. The Journal of Medicine and Life reports that electrocution can result in massive muscle and organ damage and even be fatal. 2019 Jul 1;17(1):122. doi: 10.1186/s12916-019-1356-z. We are dedicated to providing the most scientifically valid, unbiased, and comprehensive information on any given topic. St segment elevation acute myocardial infarction and complications of myocardial infarction. government site. In non-Q wave, incomplete occlusion, nontransmural MI, CK-MB peaks on the average 15 hours from onset. Doctors run CPK blood tests if a person complains of symptoms relating to muscle weakness. Creatine phosphokinase (CK) is an enzyme found mainly in the skeletal muscle, but also in the heart and brain. We use cookies on our website to give you the most relevant experience by remembering your preferences and repeat visits. Clin Chim Acta. Higher amounts of serum CK can indicate muscle damage due to chronic disease or acute muscle . In a healthy adult, the serum CK level varies with a number of factors (gender, race and activity), but normal range is 22 to 198 U/L (units per liter). Testing for high CPK levels in a blood test can help doctors determine the severity of the head injury and therefore recommend the best course of treatment.6. West J Med. The majority of competitive athletes have raised CK level in the blood (2). Doctors may check for creatine kinase levels that are above the normal range if they suspect that a person has had a stroke. Some of these are:24. A CPK blood test that shows persistently high levels of creatine kinase could be an indicator of an autoimmune condition. The CPK test is easily performed within minutes, and it does not require any special preparation. No special preparation is needed most of the time. However, it can cause worrying symptoms like:5. In benign forms of motor delay, physical and occupational therapy may promote acquisition of skills. Other than that, there is only a small risk that side-effects such as fainting, lightheadedness, infection, or excessive bleeding would happen. Pediatric reference ranges were determined on hospitalized patients using the Hoffmann approach. In another study of over 10,000 adults, overweight and obese men had almost 2 times greater odds of having elevated CK [19]. sharing sensitive information, make sure youre on a federal But opting out of some of these cookies may affect your browsing experience. Is it normal to have high CPK levels during labor? HealthHarvard. Total creatine kinase levels are reduced in the second trimester of pregnancy. Goldman-Cecil Medicine. Studies suggest that the more creatine kinase a person has within the normal range, the better their heart and muscles can function. This can impact on skeletal muscle function and cause tissue to release CK enzymes into the blood. The dominant isoenzyme was CK-MM (CK-3) in both species. The CPK normal range for a male is between 39 - 308 U/L, while in females the CPK normal range is between 26 - 192 U/L. Our specialists handle conditions ranging from the common to the most rare. The CK can help distinguish between central (where there is normal CK) and peripheral (where CK may be elevated) causes of motor delay. Creatine phosphokinase levels from the entire population of adults and children were normally disturbed, and the mean CPK levels for the eight diagnostic groups were within normal limits. The procedure is called a venipuncture. Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine. High levels of LDL, or bad cholesterol, can lead to blocked arteries and heart disease. This article discusses the test to measure the amount of CPK in the blood. The Journal of Neurosurgery reported that severe head injuries can cause higher than normal levels of CK and CK-BB in blood tests. Creatine kinase will leak into the blood when these tissues are damaged. which enables users to obtain detailed information and reports based on their genome. In individual cases, CK levels may occur that are clearly above 1000 U/L (3). Horm Res.1999;52(4):205-8. There are many causes of CPK elevation and muscle damage. the normal range for adults. Therapists may help parents feel more comfortable working with their children and achieve a greater sense of control. If total CK activity is 100 U/L or greater, then isoenzyme electrophoresis (CKE) will be performed at an additional charge. Clin Chem Lab Med. Philadelphia, PA: Elsevier; 2019:chap 98. Eur J Nutr.2017 Nov 25. Eating a healthy diet, getting enough exercise, and avoiding habits that can damage your brain are just some practical suggestions. Because your age, health history, physical activity levels, and race can affect normal CPK results, your doctor will diagnose what your CPK blood test results mean for you. CPK Blood Test: What Does It Mean If You Have High CPK Levels? If there is no evidence of heart problems or skeletal muscle breakdown, then the kidneys may be the cause of the increased levels of CKMB. Created for people with ongoing healthcare needs but benefits everyone. What are normal CK MB levels? Objectives: Functional cookies help to perform certain functionalities like sharing the content of the website on social media platforms, collect feedbacks, and other third-party features. According to research published by the University of California, omega-3 can help reduce the symptoms of a number of inflammatory diseases. Acta Obstet Gynecol Scand.1996 Mar;75(3):255-60. Align your health hacks with your genes for optimal health & cognitive function. Note: Urine the color of cola/tea, especially with muscle pain: send child immediately to the ER for urgent emergency intervention. CK catalyses the conversion of creatine and uses adenosine triphosphate (ATP) to create phosphocreatine (PCr) and adenosine diphosphate (ADP). A significant concentration of CK-MB isoenzyme is found almost exclusively in the myocardium, and the appearance of elevated CK-MB levels in serum is highly specific and sensitive for myocardial cell wall injury. This is because your body is constantly replacing and renewing dead cells. Specimen requirements. 33 yrs old Male asked about Cpk mb meaning and normal range, 1 doctor answered this and 30 people found it useful. Creatine kinase has a very short half life. Please discuss with your doctor any questions or concerns you may have. Kidney failure becomes likely, which will require dialysis or a kidney transplant. ( 28235546) Initial CK level is moderately elevated and there is a high index of suspicion for rhabdomyolysis. Cpk mb meaning and normal range. A small study with 14 men showed that sports massage 2 hours after exercise decrease CK levels [83]. These materials have been endorsed by the American Academy of Pediatrics. Out of these, the cookies that are categorized as necessary are stored on your browser as they are essential for the working of basic functionalities of the website. Am J Med Genet.1985 Sep;22(1):81-7. In a large community study of over 12,000 people in Norway, people who had elevated CK levels were re-tested after 3 days of rest. Houston KA, Gibb J, Olupot-Olupot P, Obonyo N, Mpoya A, Nakuya M, Muhindo R, Uyoga S, Evans JA, Connon R, Gibb DM, George EC, Maitland K. BMC Med. National Library of Medicine The amount of CK in the serum is reported in units (U) of enzyme activity per liter (L) of serum. Both equations were derived from large population studies and will generate an estimate of the mean GFR in a population of patients with the same age, gender, race, and serum creatinine. Because creatine kinase is a measure of muscle mass, it is not surprising that a link was found between low creatine kinase levels and higher mortality. However, some athletes show only moderate or no response (non-responders) (4). cpk normal range in child. People with higher BMI and weight have increased creatine kinase levels [4, 18]. If you feel that any of our content is inaccurate, out-of-date, or otherwise questionable, please leave a comment or contact us at support@selfdecode.com. When muscle tissue is damaged, CPK leaks into your blood. Patients having increased value for one or both. The journal Deutsches rzteblatt International reported that higher than normal CK levels are generally seen in professional or competitive athletes. Epub 2003 Dec 11. FOIA If your CK gets high because your muscles get damaged after exercise, there are some steps you can take to improve muscle recovery. This cookie is set by GDPR Cookie Consent plugin. This is an enzyme that can be found around the brain, the heart, and skeletal muscles. High CPK levels may be seen in people who have: Other conditions that may give positive test results include: Risks associated with having blood drawn are slight but may include: Other tests should be done to find the exact location of muscle damage. Myocarditis is inflammation of the heart muscle and will also cause CPK lab tests to show higher than normal results. Normal Results Total CPK normal values: 10 to 120 micrograms per liter (mcg/L) What CK levels indicates muscular dystrophy? monthly budget of middle class family. The .gov means its official. Creatine kinase, CK . Doctors report that any abnormalities in the heart muscle like inflammation or damage will cause CPK serum levels to rise.2, The most common reason for myocarditis is a viral or bacterial infection that can cause inflammation in the heart muscle. MayoMedicalLaboratories. Creatine Kinase and liver enzymes (ALT and AST): - A normal CK level with elevated ALT and AST enzymes would sway a doctor toward thinking there's a liver problem; Extraordinary kid care (Details of methodology available on request . This cookie is set by GDPR Cookie Consent plugin. Sudden weakness or numbness on one side of the body. Garlic has many beneficial properties that can help to keep your heart healthy. [2] Alterations in specific genes cause different representations of this disease. Careers. Do athletes have high CK levels? Finding which specific form of CPK is high helps determine which tissue has been damaged. However, please note that a normal CK does not rule out neuromuscular diseases such as spinal muscular atrophy; in this instance genetic testing is required to rule out the disorder. During labor, creatine kinase is released by the placenta and uterus which cause CK-MB levels to rise significantly. CK levels are around 70% higher in healthy African Americans, compared to people of European descent! Firefox. It will help your doctor to form a proper diagnosis and continue to plan an effective treatment plan. You may feel pain where the needle has been inserted into your arm, and some temporary bruising might develop in the next few days. You must consult your doctor before acting on any content on this website, especially if you are pregnant, nursing, taking medication, or have a medical condition. Carty RP, Pincus MR, Sarafraz-Yazdi E. Clinical enzymology. Normal Values for CK, CPK* Men: 5-100 IU/L: Women: 10-70 IU/L: Pregnancy: 5-40 IU/L: Normal Values for CK or CPK Isoenzymes* MM: 97%-100% : MB: Getting more exercise is one of the simple ways you can prevent a heart attack. The Journal of Nutrition reported in 2016 that garlic supplements can provide cardiovascular protection by lowering cholesterol and hypertension levels.20, Change your diet. 2016 May; 113(19): 344. SelfDecode does not treat, diagnose or cure any conditions, The effect of gestational age, birth weight, and disease on troponin I and creatine kinase MB in the first year of life. That is why men usually have higher CK values than women. Required fields are marked *. Drawbacks of CK level: 5.2k The CPK test involves inserting a needle in a vein in your arm in order for a sample of your blood to be collected. CPK levels can be excessively high if a person has suffered a heart attack which has resulted in muscle damage to the heart. Ranges were also obtained for CKMB, troponin I, and total CK. Critically ill people who are weaker (with less muscle mass) have a higher risk of dying [92]. We've got you covered. HopkinsPlus. When a muscle is damaged, CPK leaks into the bloodstream. Also, people who are untrained will experience greater spikes in CK levels due to greater muscle damage [8]. He also edits and writes articles for the IronSet blog where he shares his experiences. Because your age, health history, physical activity levels, and race can affect normal CPK results, your doctor will diagnose what your CPK blood test results mean for you. 7 Whats the normal CPK level for a blood test? Creatine phosphokinase (CPK) is an enzyme in the body. WebMD. The CK CPK blood test is used to measure the amount of creatine phosphokinase that is in the blood. Lets look in more detail at what abnormal CPK levels can mean and how doctors can interpret the results. Conclusion: 23rd ed. Therefore, its important to lower your cholesterol naturally before you may need to use statins to control cholesterol. If elevated CK persists, it is more likely to be due to an underlying health issue. You may feel slight pain when the needle is inserted to draw blood. Lab Appointments & Locations COVID-19 Testing Info Test Details Results and Follow-Up Overview Healthy and Natural World is supported by its audience. Epub 2022 Apr 21. CPK blood tests the different forms of CPK in the bloodstream and the CPK normal range varies from a male to female. The upper normal limit for men is anywhere from 200 to 395 U/L (3.4 - 6.8 ukat/L) and for women, it's up to 207 U/L (3.52 ukat/L) [ 3, 4, 5 ]. Pediatric reference ranges for creatine kinase, CKMB, troponin I, iron, and cortisol - ScienceDirect Clinical Biochemistry Volume 32, Issue 1, February 1999, Pages 77-80 Clinicals Pediatric reference ranges for creatine kinase, CKMB, troponin I, iron, and cortisol Steven J Soldin 1 2 , Jayasimha N Murthy 1 2 , Pankaj K Agarwalla 1 , Between 39 and 308 U/L. A blood sample is needed. Federal government websites often end in .gov or .mil. J Inherit Metab Dis. How to differentiate between UTI and Pregnancy Symptoms? 11th ed. Creatine kinase (CK) activity in serum is widely used to diagnose tissue damage including myocardial infarction and skeletal muscle myopathy, but it is unknown why serum CK activity is higher in apparently healthy black people of sub-Saharan African descent [1] - [4]. During a study carried out at the Montreal Children's Hospital involving measurement of serum creatine phosphokinase (CPK) levels in healthy children, it was fo [Skip to Navigation] . Creatine kinase will increase with muscle, heart, or brain damage these can be caused by an underlying disease or disorder, including: Interventions that damage tissues, such as injections into the muscles or any type of surgery, will increase CK levels [8, 57, 58]. Polymyositis is an uncommon autoimmune disorder in which the immune system attacks the muscles resulting in inflammation and the release of creatine phosphokinase (CPK). CPK-MB and Troponin I were done on day of admission and values were interpreted as normal between 0 to 25 IU and 0.00 to 0.04 IU 21 respectively. NCI CPTC Antibody Characterization Program. Adults and children: 27-31 pg Newborns: 32-34 pg Mean corpuscular hemoglobin concentration (MCHC) Adults and children: 32-36 g/dl Newborns: 32-33 g/dl White blood cell count (WBC) Adults and children >2 yrs: 5000-10,000/cm 3 Children 2 yrs: 6200-17,000/mm 3 Higher-than-normal CPK-1 levels: Because CPK-1 is found mostly in the brain and lungs, injury to either of these areas can increase CPK-1 levels. Range values vary depending on the lab doing the test. The results are known to vary from person to person, depending on different conditions and injuries that had led to the increased levels of CPK in the first place. In pathological states increased serum enzyme concentrations (probably the expression of a defect in cellular permeability) are constantly present in the Duchenne type of progressive muscular dystrophy. Frustrated by the lack of good information and tools, Joe decided to embark on a learning journey to decode his DNA and track his biomarkers in search of better health. In a healthy adult, the serum CK level varies with a number of factors (gender, race and activity), but normal range is 22 to 198 U/L (units per liter) 1. Sample requirements. Tell your health care provider about any medicines you are taking. Philadelphia, PA: Elsevier Saunders; 2017:chap 85. Higher amounts of serum CK can indicate muscle damage due to chronic disease or acute muscle injury. Referral to a specialist is indicated when a child fails to meet the motor milestones as described in the Signs of Weakness by Age surveillance aid. Your email address will not be published. A CPK blood test can also help diagnose various muscle diseases, including dermatomyositis, polymyositis, and other health issues linked to muscle breakdown. Early treatment with prednisone and sometimes additional drugs can completely reverse the muscle weakness. J Neuorsur. Which elements are bonded together to form salt? eCollection 2019. This enzyme is released by damaged muscle, and levels above 1000 U/L (5 times the upper limit of normal (ULN)) indicate rhabdomyolysis. opentable system design. Finding which specific form of CPK is high helps determine which tissue has been damaged. If you see global delay, evaluate for muscle weakness. Inflammatory diseases of muscle and other myopathies. Advertisement cookies are used to provide visitors with relevant ads and marketing campaigns. A rapid reference. If a patient has an indication for urgent referral, you should consider direct contact with the neurologists office to share concerns, as this may expedite the appointment. The long-term use of statins can mean that your blood test results show elevated CPK levels due to muscle damage that statins can cause. Pappas summarizes current literature regarding timing as follows. NCBI. If you suspect muscle weakness, include a CK as part of your evaluation. HeartOrg. High CPK levels can mean that a tissue has been damaged due to a person suffering a heart attack, stroke, or head injury. Doctors run CPK blood tests if a person complains of symptoms relating to muscle weakness. An electric shock can cause muscle and skeletal damage that can result in high CPK which can indicate the severity of tissue or muscle damage. Of course, it is essential that you inform your doctor about any prescribed and/or over-the-counter medication, including any dietary supplements that you have been taking. Creatine enzymes are released from muscles or tissues if they are injured, damaged, or die off. Biljana received her PhD from Hokkaido University. Clipboard, Search History, and several other advanced features are temporarily unavailable. Doctor, author and fitness enthusiast, Ahmed Zayed, MD, is a surgery resident with a passion for helping people live a happy healthy life. This Aid includes assessing weakness by age, clinical evaluation for muscle weakness, guidance on the use of CK testing, and the motor delay algorithm. World-class docs Most neuromuscular diseases have normal MRI of brain, but some have characteristic abnormalities. This is nothing to worry about because high CPK levels will return to the normal range after finishing exercising. 2016 Aug; 95(33): e4344. Although higher CK levels are found in athletes, conversely, high CK levels are also found in obese and overweight people. Muscular dystrophy is a group of genetic diseases that typically affects male children and will cause high CPK levels due to muscle loss. This high creatine kinase levels can also give doctors an indication of the extent of muscle damage and recommend the best course of treatment.3, A doctor may also check for abnormal CPK levels if you have symptoms of cardiovascular disease. Emery-Dreifuss MD patients can have a moderate elevation of CPK. High plasma CK, even in the normal range, may decrease the ability of our blood to clot properly. 2013 Oct-Dec; 3(4): 303312. All of our content is written by scientists and people with a strong science background. Jonathan Ritter, PharmD, PhD (Pharmacology), Inability to exercise (due to pain or weakness), Muscle injuries, physical trauma, and burns [, Genetic muscle disorder, such as muscular dystrophy (i.e Duchenne muscular dystrophy) [, Infections by viruses, bacteria, fungi, or parasites, causing muscle wasting [, Hypothermia, a dangerous drop in body temperature [, Metabolic disturbances such as hyponatremia (low sodium), hypokalemia (low, Diabetes; when it causes muscle dysfunction (myopathy) [, Some cases of autoimmune diseases when there is muscle involvement, such as lupus, rheumatoid arthritis, and celiac disease [, Fibrates, another group of drugs that decrease cholesterol [, Glucocorticoids used to decrease inflammation [, Antibiotics, antiretrovirals, and antimalarials [. Also discover related tests such as creatine kinase (CK). Those 22 children with personality disorders had significantly higher CPK levels than the other diagnostic groups. Elevated CPK - What Causes High CPK Levels? What is CPK normal range? A CPK blood test checks for levels of creatine phosphokinase (or, creatine kinase) in the blood. Read More. It was found that people who followed the Mediterranean diet were at less risk of heart disease.21, Reducing stress. The normal CPK levels are known to variate according to age and sex. High liver enzymes may show up on a routine blood test during a child's yearly checkup. The elevated Troponin I is found in the first year of life also represents new data. What are the symptoms of high CPK levels? Note that each number in parentheses [1, 2, 3, etc.] CK stands for creatine kinase, an enzyme that leaks out of damaged muscle. Our science team is put through the strictest vetting process in the health industry and we often reject applicants who have written articles for many of the largest health websites that are deemed trustworthy. 2000 Mar;38(3):187-97. doi: 10.1515/CCLM.2000.027. This cookie is set by GDPR Cookie Consent plugin. Various blood tests can help doctors determine brain and tissue damage after a stroke. Circulation. A meta-analysis of 14 studies concluded that light therapy (low-level laser therapy and/or light-emitting diode therapy) had beneficial effects on decreasing CK levels after exercise [84]. All practi-tioners are urged to consult the normal laboratory values for their local laboratory, as these may differ from those listed below. Generally, 24-204 U/L is considered normal. Comparison of the diagnostic utility of CK, CK-MB (activity and mass), troponin T and troponin I in patients with suspected acute myocardial infarction. DMD-related muscular dystrophy in Cameroon: Clinical and genetic profiles. Learn how we can help. CK levels that are too high could mean that you suffer from a thyroid disorder where your thyroid doesnt produce enough hormones. Normal CPK range for females. Studies suggest that after strenuous exercise, an increase in creatine kinase (muscle damage) can be attenuated by consuming enough carbs, protein, and antioxidants [82].